REGULATORY SYSTEM ADAPTIVE STATUS IN PERSONS WITH ACNE VULGARIS

Aim. To observe a regulatory system adaptive status (regulative adaptive ability) of patients with acne (acne vulgaris), depending on the severity of the disease: mild, moderate or severe.

Materials and methods. Observations were made on 85 boys and girls aged 13-18 years suffering from acne (acne vulgaris). Along with the clinical methods of examination, the observed gave their informed consent to conduction of a trial of cardio-respiratory synchronism, which was performed on a certified device "VNS-Micro" (manufactured by Neurosoft LLC,Ivanovo) by means of a system for detection of cardio-respiratory synchronism in humans. The regulatory adaptive ability was evaluated by index. Statistical analysis of the results of the study was conducted using programmes “Statistika 6.0 for Windows”. To determine significance of differences in mean values in paired comparisons, the Student's t-test was used for p <0.05.

Results. Patients with mild acne demonstrated the regulatory system adaptive status index (M±m) being 68.5±0.3, SD=1.6, their regulative adaptive ability was good. Patients with moderate acne demonstrated the regulatory system adaptive status index being 37.4±0.4, SD=2.1, their regulative adaptive ability was satisfactory. Patients with severe acne – 16.6±0.4, SD=2.1, their regulative adaptive ability was low.

Conclusion. The harder for acne, the lower the regulative adaptive features of observed individuals.