<i>Commentary</i>: Unexpected Novel Chemical Weapon Agents Designed by Innocuous Drug-Development AI (Artificial Intelligence) Algorithm

Raffa, Robert B. and Pergolizzi, Joseph V. and Miller, Thomas and Motto, Daniel (2022) <i>Commentary</i>: Unexpected Novel Chemical Weapon Agents Designed by Innocuous Drug-Development AI (Artificial Intelligence) Algorithm. Pharmacology & Pharmacy, 13 (07). pp. 225-229. ISSN 2157-9423

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Abstract

Recent publications reveal the disturbing information that a minor edit to an algorithm being used for designing legitimate drug candidates redirected the program in a way that resulted in the surprising design of novel chemical warfare agent candidates. Although this outcome was not the result of nefarious intent, and appropriate chemical defense authorities were notified, the potential implications of some misapplication of a drug-design algorithm for nefarious purposes are clear. This Commentary summarizes how otherwise benign Artificial Intelligence (AI) algorithms used for drug discovery can be easily reversed to design novel chemical warfare agents for which no effective antidote will be available, or perhaps even envisioned.

Item Type: Article
Subjects: Lib Research Guardians > Chemical Science
Depositing User: Unnamed user with email support@lib.researchguardians.com
Date Deposited: 24 Feb 2023 09:25
Last Modified: 29 Jul 2024 05:43
URI: http://eprints.classicrepository.com/id/eprint/213

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